Summary
The presence of specific antigens was studied in certain fractions of mice tumors, which were induced and transplanted on purebred animals and, thus, had no isogenic variations.
It was established by anaphylactic reaction with desensitization in guinea pigs that there is a specific antigen present in the fractions of mitochondria, microsome, globulin and methanol precipitate of the hepatoma tissue and breast cancer in mice C3HA. This antigen differed from the antigens which were present in the same fractions obtained from the normal liver or a mixture of organs of healthy mice.
The presence of specific tumor antigens in the cellular organoids, as well as in the proteins of the hyaloplasm shows the widespread distribution of this antigen in various parts of the tumor cell.
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Levina, D.M., Artamonova, V.A. The study of antigenic properties of certain corpuscular and soluble fractions isolated from tumors of inbred mice. Bull Exp Biol Med 46, 973–978 (1958). https://doi.org/10.1007/BF00787338
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DOI: https://doi.org/10.1007/BF00787338