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The functional state of the nerve-muscle preparation in the intact organism under conditions of disturbed circulation

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Experiments were staged on rabbits with the aid of a method of incomplete separation of the muscle and placing it into a cutaneous muff with intact vascular and nervous connections. The lability and contractile property of the nerve — muscle preparation, preserved in the body, was studied in the state of ischemia. The decrease of excitability, increase of the absolute refractory phase and shortening of the phase of maximal summation were noted under the effect of ischemia. These changes progressed after development of the block of the neuromuscular transmission and an acute decrease of lability was added. Complex reactivity of the muscle appeared in 1–1 1/2 to 2 hours of ischemia.

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Literature Cited

  1. S. V. Verzilova and A. N. Magnitskii, Subordination in the Nervous System and its Significance in Physiology and Pathology, In Russian. Moscow, 1948, pp. 234–246.

  2. A. M. Vorob'ev, Fiziol. Zhurn. SSSR 17, 5, pp. 972–982 (1934).

    Google Scholar 

  3. A. V. Dokukin, Biull. Eksptl. Biol. i Med. No. 40, pp. 71–73 (1953).

    Google Scholar 

  4. A. V. Dokukin, Biull. Eksptl. Biol. i Med. No. 11, pp. 34–38 (1956). Original Russian pagination. See C. B. Translation.

    Google Scholar 

  5. B. A. Dolgo-Saburov and V. N. Chernigovskii, Collection Dedicated to the 50th Anniversary of V. N. Tonkov, In Russian, Leningrad, 1947, pp. 35–56.

  6. P. O. Makarov, Trudy Leningrad Obshchestva Estestvoisp 67, 1, pp. 3–5 (1939).

    Google Scholar 

  7. O. V. Plotnikova, Questions in Physiology of the Nervous and Muscular Systems, In Russian. Moscow-Leningrad, 1950, pp. 179–196.

  8. A. Rizhkov, N. Sobolev, G. Ermolaev and I. Kaveshnikov, Questions in General Physiology of the Nervous System, In Russian. Leningrad, 1941, pp. 158–166.

  9. G. T. Semenova, Seventh All-Union Congress of Physiologists, Biochemists and Pharmacologists, In Russian. Moscow, 1947, pp. 79–81.

  10. N. A. Tikhomirova, Questions in Physiology of the Nervous and Muscular Systems, In Russian. Moscow-Leningrad, 1950, pp. 282–299.

  11. I. M. Tylevich, Mechanisms of Pathological Reactions, In Russian. v. 16–20, Leningrad, 1950. pp. 445–457.

  12. G. Bourguignon and H. Laugier, Arch. Intern. Physiol. v. 21, p. 265 (1923).

    Google Scholar 

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Authors and Affiliations

  1. Laboratory of Pathophysiology and Pharmacology of the Cardiovascular System of the Institute of Pharmacology and Chemotherapy, AMN SSSR, USSR

    A. V. Dokukin

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  1. A. V. Dokukin
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Dokukin, A.V. The functional state of the nerve-muscle preparation in the intact organism under conditions of disturbed circulation. Bull Exp Biol Med 46, 948–952 (1958). https://doi.org/10.1007/BF00787331

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  • DOI: https://doi.org/10.1007/BF00787331

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