Summary
Albino rats were used in a study of the effect produced by the two hormones of the anterior pituitary lobe on repair processes in skin wounds. STH caused increased amounts of glycogen and RNP to accumulate in the young cells and retarded the differentiation of the blood and tissue cells concerned in the formation of granulation tissue; the result was an increased proliferation of the young epithelium. ACTH stimulated the differentiation and activity of the young cells with the result that the ratio of ground substance to cells was increased. Consequently the trophic function of the young epithelium was reduced, and the whole repair process was depressed.
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Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 55, No. 6, pp. 92–96, June, 1963
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Voitkevich, A.A. The influence of STH and ACTH on repair processes in wounds. Bull Exp Biol Med 55, 674–677 (1964). https://doi.org/10.1007/BF00786814
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DOI: https://doi.org/10.1007/BF00786814