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Investigation of the mechanism of chemoreception

Reprot V. The effect of tetraethylammonium on the ability of the small intestine receptors to perceive various chemical stimuli

  • Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

A study was made of the effect produced by TEA on the reception of ACh, nicotine, and acids. As established, TEA blocked the reception of nicotine by the receptors, did not affect the action of acids, and only partially depressed the ACh reception; the part of the reaction in response to ACh which remained after the TEA action was blocked in this case with ATP. A conclusion was drawn that in effecting the reaction of the given area to ACh considerable significance is played both by this direct action upon the receptors and by their mechanical stimulation as a result of musculature spasm; it also followed that the ACh transmission in this area was absent.

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Authors and Affiliations

  1. The Laboratory of General Physiology of the Institute of Normal and Pathological Physiology of the Akad. Med. Nauk SSSR, Moscow

    N. A. Anikina

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  1. N. A. Anikina
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Anikina, N.A. Investigation of the mechanism of chemoreception. Bull Exp Biol Med 55, 614–618 (1964). https://doi.org/10.1007/BF00786798

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  • DOI: https://doi.org/10.1007/BF00786798

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