Summary
In mice of the new mutation known as short-leg (symbol sl) there are skeletal anomalies of the limbs, and the bones both the fore- and hindlimbs, especially the fibula, are reduced, the tibia is strongly curved, there is a disturbance of the ankle joint, and a distinct brachydactyly. There are no visible bone anomalies in the rest of the skeleton, no disturbances of the viscera, and viability and fertility are normal. The anomaly is inherited as an autosomal recessive with complete penetrance, and is not linked with albinism.
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Literature Cited
N. Bateman, J. Anat. (Lond.), Vol. 88, p. 212 (1954).
T. C. Carter, Heredity, Vol. 2, p. 405 (1948).
Idem, J. Genet., Vol. 50, p. 277 (1951).
P. Forsthoefel, J. Morph. Vol. 102, p. 247 (1958).
H. Grüneberg, The Genetics of the Mouse. Hague (1952).
Idem H. Grüneberg, An Annotated Catalogue of the Mutant Genes of the House Mouse, London (1956).
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Vasil'eva, N.A., Konyukhov, B.V. A genetic analysis and morphological description of a line of mice showing the mutation short-leg. Bull Exp Biol Med 53, 603–605 (1963). https://doi.org/10.1007/BF00786756
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DOI: https://doi.org/10.1007/BF00786756