Summary
Histochemical analysis of polysaccharides was done in internal organs in experimental hypothyroidism. A considerable rise in glycogen content was noted in the parenchyma of the liver and heart; glycogen distribution in the cardiac muscle fibers was uneven, in the form of separate large foci, surrounded by mucoid edema of the stroma. In the interstitial tissue of internal organs accumulation of acid mucopolysaccharides is observed, the composition of which varies in different organs (in the heart — preponderantly hyaluronic acid, in the kidneys — chondroitinsulfate C, etc). Mucoproteid accumulation is noted in the blood plasma and lymph in experimental hypothyroidism cases.
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Leites, F.L. Histochemical peculiarities of carbohydrate metabolism in experimental hypothyroidism. Bull Exp Biol Med 53, 531–535 (1963). https://doi.org/10.1007/BF00786738
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DOI: https://doi.org/10.1007/BF00786738