Peculiarities in the course of the pyretic reaction associated with various functional states of the alimentary center

  • L. I. Gorbatsevich
Pathological Physiology and General Pathology


Chronic experiments were performed on 2 gastrectomized dogs. A study was made of the development and the course of experimental pyretic reaction and of the changes in the gastric secretion in various functional conditions of the alimentary center. After a 24- and 48-hour starvation and an additional stimulation by teasing dogs with a piece of meat a marked rise of the alimentary excitation of animals was noted, manifested in the rise of the motor and secretory reaction (a rise of the gastric juice secretion and of its acidity); the administration of a pyrogenic stimulus against this background causes a more rapid and marked temperature rise in comparison with control experiments. With an excessive rise of alimentary excitability (after 4 days of starvation) there is either not a very pronounced increase or even some reduction of pyrexia.

The data obtained show the significance of the functional state of alimentary center for the development and the course of pyrexia.


Public Health Functional State Control Experiment Temperature Rise Gastric Juice 
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Copyright information

© Consultants Bureau Enterprises, Inc. 1963

Authors and Affiliations

  • L. I. Gorbatsevich
    • 1
  1. 1.Division of General Pathology of the Institute of Experimental Medicine of the Akad. Med. Nauk SSSRLeningrad

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