Summary
In examining the total cholesterol and phospholipid, content as well as cholesterol-phospholipid coefficient in 170 healthy female rabbits of various age distinct differences in these lipid metabolic indices was noted, peculiar to diverse ages. Cholesterol and cholesterol-phospholipid coefficients were much higher in rabbits of reproductive age, than in those of other age groups. Phospholipid content decreased with the age. In cholesterol-fed animals the rise of cholesterolemia, and of cholesterol-phospholipid coefficient, as well as the degree of aortic atherosclerosis development were greater with advancing age.
These data demonstrate that the age factor affects the blood serum lipid content and also the intensity of alimentary cholesterol atherosclerosis developing in animals.
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Nasledova, I.D., Rafal'skii, Y.D. The effect of the age factor in the development of experimental atherosclerosis. Bull Exp Biol Med 53, 513–516 (1963). https://doi.org/10.1007/BF00786734
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DOI: https://doi.org/10.1007/BF00786734