Conditions of reproduction of avian myeloblastosis virus as a source of revertase

  • N. A. Graevskaya
  • A. F. Sito
  • A. L. Dumina
Biochemistry and Biophysics


The conditions for reproduction of avian myeloblastosis virus, as the main source for isolation of RNA-dependent DNA polymerase, were studied in connection with the “revertase” project. Eight Soviet lines of hens were used. Day-old chicks received an intracardiac or intraperitoneal injection of 0.1 ml of the virus. The titer of the virus was determined with reference to its ATPase activity. Of the strains studied, highest susceptibility to myeloblastosis (up to 75%) and highest titers (over 1011) were observed in lines from the En'ya cross.

Key Words

avian myeloblastosis virus hens susceptibility 


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Copyright information

© Pelnum Publishing Corporation 1975

Authors and Affiliations

  • N. A. Graevskaya
    • 1
  • A. F. Sito
    • 1
  • A. L. Dumina
    • 1
  1. 1.Laboratory Group for Diagnostic Preparations, Institute of Poliomyelitis and Virus EncephalitisAcademy of Medical Sciences of the USSRMoscow

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