Cell division and vitamin A
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Vitamin A injected into white mice stimulates cell division. The epithelium of the intestines is the most sensitive to the vitamin. Vitamin A deficiency does not lead to any considerable changes in the number of mitoses in the tissues but the regulation of cell division is strongly disturbed. In cases of avitaminosis even such a powerful stimulator of mitosis as thyroidin fails to increase mitotic activity. The presence of vitamin A in the tissues is indispensable for the stimulative effect of thyroidin on cell division. Experiments on mice with Kroker's sarkoma demonstrated that vitamin A does not change the intensity of turnor cell division, since in turnors that process is out of control of the neurohumoral system which regulates the mitotic activity in normal tissues.
KeywordsPublic Health Cell Division Normal Tissue Mitotic Activity Considerable Change
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- I. A. Alov, Ilyull. Eksptl. Biol. i Med. Vol. 40, No. 12, pp. 47–50.Google Scholar
- I. A. Alov, Voprosy Onkol. 1955, Vol. 1, No. 6, pp. 40–45.Google Scholar
- I. A. Alov, Doklady Akad. Nauk SSSR 1956, Vol. 107, No. 5, pp. 745–747.Google Scholar
- I. A. Alov, in the book: Works of the Khabarovsk Medical Institute. 1956, Vol. 15, pp. 63–71. In Russian.Google Scholar
- P. P. Smilyanskaya and K. Z. Tulchinskaya, in the book: Vitamins in Theory and Practice. Moscow 1953, pp. 152–153. In Russian.Google Scholar
- L. V. Suvorova, Reactive Inhibition of Cell Division in Animals and the Development of a Capacity for it in Ontogenesis, Dissertation, Leningrad 1955. In Russian.Google Scholar
- E. Bujard, W. Jadassohn and R. Brun, Compt. rend. soc. biol. 1954, Vol. 148 No. 9–10, pp. 778–780. In Russian.Google Scholar
- R. F. Krause and H. B. Pierce, Arch. Biochem. 1948, Vol. 19, pp. 145–148.Google Scholar
- A. Studer and I. A. Frey, Dermatologica, 1952, Bd. 104, N. 1, S. 1–18.Google Scholar