Summary
The level and pulse variations of the arterial and intracranial pressure in animals were studied for evaluation of the changes of the tone of brain vessels which take place under the effect of various pharmacological substances.
Parallel registration of the variations of intracranial and arterial pressure was done by the tensiometric method. A detailed description of the appratus and the scientific basis for the use of this method are presented in this paper.
It was established that pulse variations of the intracranial pressure which occur as a result of pulsation of the brain vessels appear only in such conditions in which the cranium is hermetic.
The curves of intracranial and arterial pressure of a cat are presented as an example. These curves were obtained under the effect of substances which greatly reduce the tone of the brain vessels (carbon dioxide) or those which increase it (oxygen).
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Literature Cited
A. A. Kedrov and A. I. Naumenko, Problems of the Physiology of the Intracranial Circulation and Their Relevance to Clinical Practice, in Russian Experimental investigation, Leningrad 1953.
B. N. Klosovskii, Circulation of Blood in the Brain, in Russian Moscow 1951.
Iu. Iu. Kolchinskii, I. G. Korovianskii and V. A. Orlov.. Zavodskaia Laboratoriia, 12, 6 7–8 (1946).
Kedi, Piezoelectricity and Its Practical Application, in Russian Moscow 1949.
M. E. Marshak, Piezoelectric Transducers for Recording the Pulse in the Vessels of the Finger and the Lobe of the Ear. Biull. Eksptl. i. Med. 5, 75–77 (1956). Original Russian pagination. See C. B. Translation.
H. Sigward, Langenbecks Arch. and Deut. Z. Chir. 1954, Vol. 278, No. 2, pp. 115–122.
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Liberman, T.I. A method for studying cerebral vascular tone variations in animals. Bull Exp Biol Med 45, 115–118 (1958). https://doi.org/10.1007/BF00785991
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DOI: https://doi.org/10.1007/BF00785991