Summary
A modified method of neutral red staining of the organs of cold-blooded animals in situ was used and the effect of lead nitrate on various cells was studied. The following threshold paranecrotic doses were established for this salt: 3 mg per g of body weight of liver cells, 7 mg per g for cells of kidney tubules and 10 mg per g for sympathetic nerve cells. Paranecrotic changes were not revealed in the sensory nerve cells of the spinal ganglia, although reflex activity of the laboratory animals was depressed. The modified method of staining in vivo is recommended for use in toxicology.
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Gramenitskii, E.M. Effect of lead nitrate on the supravital staining of cells of poikilotherms. Bull Exp Biol Med 45, 97–100 (1958). https://doi.org/10.1007/BF00785986
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DOI: https://doi.org/10.1007/BF00785986