Bulletin of Experimental Biology and Medicine

, Volume 45, Issue 1, pp 12–16 | Cite as

Application of static muscular contraction to the analysis of the mechanism of vomiting

  • A. A. Sukhanov


Static muscular work which consisted in holding a load on the back inhibited the act of vomiting which was induced by apomorphine or by stimulation of the stomach receptors by a solution of potassium chloride. The act of vomiting was inhibited by placing the dog under conditions in which the experiment was formerly conducted (following several experiments with the load, i.e., by way of conditioned reflex). Various components of the act of vomiting were inhibited differently. The mildest depression was found in the activity of somatic musc les (abdominal press). The autonomic component of the act of vomiting (secretion of saliva, dyspnea, stomach contraction, increased rate of cardiac contractions) was only slightly inhibited. With increase of inhibition (anesthesia) the reactions of blood pressure and respiration were found to be the most stable components out of the whole autonomic complex of vomiting reactions. A definite sequence of introduction of various components of the act of vomiting was established in experiments without the load. Several new suggestions are made concerning the regulation of the act of vomiting.


Public Health Blood Pressure Chloride Potassium Muscular Contraction 
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Copyright information

© Consultants Bureau 1958

Authors and Affiliations

  • A. A. Sukhanov
    • 1
  1. 1.Sverdlovsk Medical InstituteSverdlovskUSSR

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