Bulletin of Experimental Biology and Medicine

, Volume 54, Issue 1, pp 761–762 | Cite as

Effect of noradrenalin on duration of local anesthesia

  • A. S. Kucheruk
Pathological Physiology and General Pathology


Experiments were staged on guinea pigs and rabbits. A study was made of the peculiarities of the effect of noradrenaline on the anesthetizing action of Novocain, bencaine, dicaine, and cocaine. Prolongation of the local anesthetizing effect of Novocain and bencaine withnoradrenaline in infiltration anesthesia is slightly less than that of adrenaline. During terminal anesthesia, investigated on the rabbit cornea, noradrenaline, in distinction to adrenaline, had no significant effect on the duration of the anesthetizing action of dicaine and cocaine.


Public Health Cocaine Noradrenaline Adrenaline Local Anesthesia 
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Copyright information

© Consultants Bureau Enterprises, Inc. 1963

Authors and Affiliations

  • A. S. Kucheruk
    • 1
  1. 1.Department of Pharmacology of the Ternopol Medical InstituteTernopolUSSR

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