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Age changes in the lipofuscin content of the human heart muscle

  • Microbiology and Immunity
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Bulletin of Experimental Biology and Medicine Aims and scope

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Ontogenetic dynamics of lipfuscin in the human heart muscle were studied by the method of planimetric measurements. The hearts of one hundred cadavers of the age from 28 weeks up to 82 years were investigated. Beginning with the second decade of life lipofuscin is present on the myocardium of every individual, no matter what the cause of his death was: an occasional trauma or an infectious disease. Deposition of lipofuscin is most intense during the first half of the life span (up to 40 years), most of all, at the beginning of its appearance. Data collected indicate that lipofuscin deposition is a physiological phenomenon and is not caused by aging processes of the organism.

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Authors and Affiliations

  1. Department of General Biology, the I. M. Sechenov, Order of Lenin, 1st Moscow Medical Institute, Moscow, USSR

    T. N. Ulissova

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  1. T. N. Ulissova
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Ulissova, T.N. Age changes in the lipofuscin content of the human heart muscle. Bull Exp Biol Med 43, 636–639 (1957). https://doi.org/10.1007/BF00785753

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  • DOI: https://doi.org/10.1007/BF00785753

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