The effect of functional loading on liver regeneration in rats

  • B. P. Solopaev
Experimental Biology


Ninety albino rats with the large left liver lobe extirpated were sustained on various diets (control, sparing and choleretic). In rats fed a choleretic diet regencration of the liver was most complete. In one week after the operation the initial relative weight of the liver was already restored, while in the other groups restoration took place only after two weeks.

Restoration of the weight of the liver was due to an increase in the number of liver cells.

Thus, an enhanced functional load of the liver stimulates its regeneration.


Public Health Liver Cell Relative Weight Liver Regeneration Liver Lobe 
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Copyright information

© Consultants Bureau 1957

Authors and Affiliations

  • B. P. Solopaev
    • 1
  1. 1.Laboratory of Growth and Development Institute of Experimental BiologyUSSR Academy of Medical SciencesMoscow

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