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The effect of functional loading on liver regeneration in rats

  • B. P. Solopaev
Experimental Biology

Summary

Ninety albino rats with the large left liver lobe extirpated were sustained on various diets (control, sparing and choleretic). In rats fed a choleretic diet regencration of the liver was most complete. In one week after the operation the initial relative weight of the liver was already restored, while in the other groups restoration took place only after two weeks.

Restoration of the weight of the liver was due to an increase in the number of liver cells.

Thus, an enhanced functional load of the liver stimulates its regeneration.

Keywords

Public Health Liver Cell Relative Weight Liver Regeneration Liver Lobe 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature Cited

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    M. A. Vorontsova and L. D. Liozner, Physiological Regeneration, Moscow 1955, In Russian.Google Scholar
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    P. G. Podzolkov, The Morphological Changes in Certain Parenchymatous Organs Caused by a Protein Deficient Diet, in Russian 1948.Google Scholar
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    A. Brues, D. Drury and M. Brues, Arch. Pathol. 1936, Vol. 22, N. 5, S. 658–673.Google Scholar
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    Davis and Whipple, Liver Regeneration Following Chloroform Injury as Influenced by Various Diets. Arch. int. Med., 1919, Vol. 23, 689.Google Scholar
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    JAMA, 1914, Vol. 62, p. 895 cited by A. Brues, D. Drury and M. Brues, 1936).Google Scholar

Copyright information

© Consultants Bureau 1957

Authors and Affiliations

  • B. P. Solopaev
    • 1
  1. 1.Laboratory of Growth and Development Institute of Experimental BiologyUSSR Academy of Medical SciencesMoscow

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