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Alterations of hemodynamic indicators and of the electrocardiogram produced by experimental disturbance of the coronary circulation

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Dogs were used to create infarcts of the anterior myocardial wall. The descending branch of the left coronary artery was ligated either near its origin or cise at juncture of middic and distal thirds. The animals were observed for 40 days postoperatively and then sacrificed for complete cardiac studies. The EKG, the B.P. and heart rate were taken throughout this experimental series.

Atropine was used to abolish extrasystoles. The hemodynamic alterations were transient while the EKG tan the course usual for this type of infarct.

It is suggested that the recurrent nerve mediates heterotopic foci of cardiac excitation.

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Authors and Affiliations

  1. Pharmacology Department, Voronezh Medical Institute, Voronezh, USSR

    V. V. Gatsura

Authors
  1. V. V. Gatsura
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Gatsura, V.V. Alterations of hemodynamic indicators and of the electrocardiogram produced by experimental disturbance of the coronary circulation. Bull Exp Biol Med 43, 584–589 (1957). https://doi.org/10.1007/BF00785743

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  • DOI: https://doi.org/10.1007/BF00785743

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