Abstract
Experiments on CBA mice showed that adult animals injected intravenously with BCG mycobacteria in a dose of 2 mg 12 months after thymectomy died within 2.5 months from disseminated BCG infection against the background of depression of hypersensitivity of delayed type. Mice undergoing a mock operation developed the ordinary BCG vaccination process.
Similar content being viewed by others
Literature Cited
M. M. Averbakh, Yu. M. Galkin, V. I. Litvinov, et al., Byull. Éksp. Biol. Med., No. 6, 719 (1976).
M. M. Averbakh and V. I. Litvinov, The Immunobiological Basis of Vaccination Against Tuberculosis [in Russian], Moscow (1970).
Yu. M. Galkin and V. G. Dobkin, Éksp. Khir., No. 3, 26 (1975).
F. M. Collins, C. C. Congdon, and N. E. Morrison, Infect. Immun.,11, 57 (1975).
A. J. Crowle, J. Allergy,30, 442 (1959).
G. Harris, Immunology,29, 469 (1975).
K. Shortman, H. Boehmer, J. Lipp, et al., Transplant. Rev.,25, 163 (1975).
Rights and permissions
About this article
Cite this article
Moroz, A.M., Galkin, Y.M., Litvinov, V.I. et al. Lethal BCG infection in thymectomized mice. Bull Exp Biol Med 82, 1828–1829 (1976). https://doi.org/10.1007/BF00785709
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00785709