Abstract
The toxic properties of the organs and activity of proteolytic enzymes in them were studied in experiments on germfree rats after thermal burns. In the absence of a pathogenic microflora a state of toxemia was found to develop and the proteolytic enzyme activity was increased. The intensity of the toxic and catabolic reactions depended on the severity of the burns. The toxic manifestations and increase in proteolysis in the germfree rats were in some cases more marked than in ordinary animals. It is concluded that tissue sources of toxic products play an important role in burns.
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Zaets, T.L., Koryakina, I.K., Kotkina, T.I. et al. Toxicity and proteolysis in germfree rats with thermal burns. Bull Exp Biol Med 82, 1803–1805 (1976). https://doi.org/10.1007/BF00785700
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DOI: https://doi.org/10.1007/BF00785700