Abstract
The dynamics of the number of colony-forming units (CFU) in the bone marrow of CBA mice after receiving third-degree thermal burns covering 15% of the body surface was studied by the exogenous splenic colony method. The number of CFU in the bone marrow of the mice was reduced by 41–52% on the 4th and 16th days after burning. Thymus cells of intact mice, if injected simultaneously with bone marrow of the burned mice, increased the number of exogenous splenic colonies formed in the recipients. The results suggest that not only is the number of CFU reduced in the bone marrow after burns, but also the number of thymus-dependent cells necessary for normal colony formation.
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Literature Cited
V. G. Morozov and V. Kh. Khavinson, Éksp. Khir., No. 2, 49 (1974).
A. M. Poverennyi, O. V. Semina, and A. G. Konoplyannikov, Dokl. Akad. Nauk SSSR,223, 1248 (1975).
M. E. Farrel, N. K. Day, V. Tsakraklides, et al., Surgery,73, 697 (1973).
B. I. Lord and R. Schofield, Blood,42, 395 (1973).
E. A. McCulloch and J. E. Till, Radiat. Res.,16, 822 (1962).
A. M. Munster and S. E. Gressitt, Proc. Soc. Exp. Biol. (New York),143, 106 (1973).
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Zherbin, E.A., Semina, O.V., Neprina, G.S. et al. Colony-forming ability of the bone marrow in mice after burn trauma. Bull Exp Biol Med 82, 1778–1779 (1976). https://doi.org/10.1007/BF00785691
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DOI: https://doi.org/10.1007/BF00785691