Abstract
In dogs receiving large doses of reserpine hyponatriemia, hypokaliemia, oliguria, a reduction in the renal blood flow and in the sodium and potassium excretion, together with abolition of the inhibitory effect of the splanchnic nerve on the function of the glomerular and tubular portions of the nephron are observed as the result of functional insufficiency of the sympathetic innervation of the kidneys through the development of catecholamine deficiency.
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Literature Cited
M. I. Mavrin, Fiziol. Zh. SSSR, No. 10, 1602 (1973).
R. S. Orlov, The Physiology of Smooth Muscle [in Russian], Moscow (1967).
J. Disalvo and F. Colin, Proc. Soc. Exp. Biol. Med. (New York),136, 150 (1971).
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Mavrin, M.I. Mechanism of the influence of sympathetic nerves on kidney function. Bull Exp Biol Med 82, 1129–1130 (1976). https://doi.org/10.1007/BF00785534
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DOI: https://doi.org/10.1007/BF00785534