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Comparison of injury to sexually immature and mature rats by high doses of x-rays

  • Experimental Biology
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The effect of large x-rays doses upon young rats, aged from 25 to 30 days, was compared with that provoked in 3–4-month-old animals (sexually mature). Age was an important factor predetermining the extent of radiation injury. The role of this factor is manifested in the wide range of doses—from 10,000 to 50,000 r. Immature rats are more vulnerable than the sexually mature animals. The development of the so-called acutest form of radiation sickness deserves special attention. A shock-like condition, paralyses, convulsions and other symptoms occurred earlier and were more severe in the sexually immature rats. The age differences diminish with the increase of the dose. The threshold dose is probably about 50,000 r.

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Authors and Affiliations

  1. Department of Medical Radiology, S. M. Kirov Order of Lenin Leningrad State Postgraduate Medical Institute, Leningrad, USSR

    V. V. Kholin

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  1. V. V. Kholin
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Kholin, V.V. Comparison of injury to sexually immature and mature rats by high doses of x-rays. Bull Exp Biol Med 50, 1313–1316 (1961). https://doi.org/10.1007/BF00785392

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  • DOI: https://doi.org/10.1007/BF00785392

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