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The effect of sodium nucleate on the course and issue of leukopenia induced by Tetrathione (tetramethylthiuram disulfide)

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Tetrathione introduced into the stomach of rabbits daily for four consecutive days, in a dose of 40 mg/kg, provokes a granulocytic type of leukopenia which fails to disappear spontaneously. Sodium nucleate, injected subcutaneously for four consecutive days, once daily, in a dose of 30 mg/kg, does not improve the state of leukopenia provoked by Tetrathione.

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Authors and Affiliations

  1. Department of Pharmacology of the Voronezh Medical Institute, Voronezh, USSR

    M. V. Korablev

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  1. M. V. Korablev
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Korablev, M.V. The effect of sodium nucleate on the course and issue of leukopenia induced by Tetrathione (tetramethylthiuram disulfide). Bull Exp Biol Med 50, 1289–1292 (1961). https://doi.org/10.1007/BF00785386

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  • DOI: https://doi.org/10.1007/BF00785386

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