Summary
Until now all attempts to find a cerebroside-splitting enzyme system in the brain have remained unsuccessful. Thannhauser and Reichel observed the splitting of cerebrosides by a brain tissue extract in the presence of SH-groups. The reaction was evaluated by the rise in the amount of reducing substances in an incubated mixture. When reproducing the above experiments, the authors obtained negative results when galactose, split from cerebrosides, was determined by the specific reaction for sugar (with anthrone reagent). The cerebroside-splitting enzymes in the brain of animals probably belong to the galactosidase type.
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Morozova, M.S., Promyslov, M.S. Enzymic decomposition of the cerebrosides of the brain. Bull Exp Biol Med 50, 1275–1278 (1961). https://doi.org/10.1007/BF00785383
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DOI: https://doi.org/10.1007/BF00785383