Summary
Seasonal variations of the BMR were established in rats; they were more pronounced in sexually immature than in adult or old animals. The sexually immature rats reacted less to thyroxin than did the adult or old animals. The reaction to thyroxin was greater in winter. In a number of experiments the response was diminished or even paradoxical when the initial metabolic rate was high.
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Al'khimenyuk, V.P. The effect of thyroxin on gaseous exchange in white rats of various age groups. Bull Exp Biol Med 50, 1246–1248 (1961). https://doi.org/10.1007/BF00785377
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DOI: https://doi.org/10.1007/BF00785377