Summary
The author studied the effect of morphine (2 and 5 mg/kg), promedol (1 and 3,5 mg/kg) and phenadone (1 mg/kg) on the reflex changes of the blood pressure after stimulating the pericardium and the area of the hilum of the lung at normal temperature and in hypothermia (30–32°C and 25–27°C).
Experiments were performed on cats. Analgesics intensify the depressor vascular reflexes at normal temperatures; at lower temperatures this action is less pronounced. The change in the analgesic effect on the interoceptive reflexes from the thoracic organs in hypothermia should be regarded as the result of the altered functional condition of the central links in the reflex arc due to lowered body temperatures.
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Kovalev, G.V. The effect of analgesics on reflexes from the pericardium and the hilar region of the lungs during hypothermia. Bull Exp Biol Med 48, 1234–1237 (1959). https://doi.org/10.1007/BF00785179
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DOI: https://doi.org/10.1007/BF00785179