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24-hour rhythm of cell multiplication in rat epidermis during healing of skin wounds

  • Experimental Biology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Observations revealed that cell multiplication follows a 24-hour rhythm in the epidermis adjacent to a skin wound on the rat's back. The greatest differences between the mitotic activities at different stages of wound healing (on the first, third, and fifth day of regeneration) were observed at the time when the number of cell divisions was maximal, i. e., in the early morning hours. No. 24-hour rhythm was seen in the mitotic activity of regnerating epidermis directly over the wound.

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Authors and Affiliations

  1. Laboratory of Histophysiology of the Institute of Experimental Biology of the AMN SSSR, Moscow

    M. T. Gololobova

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  1. M. T. Gololobova
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Gololobova, M.T. 24-hour rhythm of cell multiplication in rat epidermis during healing of skin wounds. Bull Exp Biol Med 50, 1088–1090 (1961). https://doi.org/10.1007/BF00784887

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  • DOI: https://doi.org/10.1007/BF00784887

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