Skip to main content
Log in

On the immunologic characteristics of serum proteins

Part 1. Induction of anaphylaxis by isolated fractions of blood serum proteins

  • Microbiology and Immunology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Preparatory isolation of electrophoretically pure protein fractions from normal horse serum was carried out with the help of apparatus of Kunkel type in a starch block (1×13×26 cm) with 450 v, 10 ma during 48 hours.

Experiments on guinea pigs with production of active anaphylaxis have shown that albumins and globulins possess different anaphylactogenic specificity, while individual fractions of globulins possess identical immunogenic properties and are capable of giving cross anaphylactic reactions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature Cited

  1. N. A. Gorbunova and T. M. Tsipin, Byull. Éksp. Biol. Med.36, 10, 46 (1954).

    Google Scholar 

  2. S. Ya. Kaplanskii, A. E. Gurvich and L. K. Starosel'tseva, Biokhimiya23, 1, 114 (1958). Original Russian pagination. See C. B. translation.

    Google Scholar 

  3. Yu. A. Khavkin, in: Scientific Works of Students of Tashkent Medical Institute [in Russian] (1956) p. 23.

  4. Svingendow, et al., as cited by N. A. Gorbunova and T. M. Tsipin.

  5. G. Berg, F. Scheiffarth, H. Gotz, et al., Klin. Wschr.37, 144 (1959).

    Google Scholar 

  6. O. H. Lowry, N. J. Rosebrough, A. L. Farr, et al., J. Biol. Chem.193, 265, (1951).

    Google Scholar 

  7. J. Oudin, Ann. Inst. Pasteur85, 336 (1953).

    Google Scholar 

  8. R. J. Slater, Arch. Biochem. a. Biophys.59, 33 (1955).

    Google Scholar 

  9. C. A. Williams and P. Grabar, J. Immunol.74, 404 (1955).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tatarinov, Y.S. On the immunologic characteristics of serum proteins. Bull Exp Biol Med 50, 1069–1071 (1961). https://doi.org/10.1007/BF00784882

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00784882

Keywords

Navigation