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The effect of carbon dioxide gas on the content of ammonia, glutamine, and urea in the blood of amimals after injection of solutions of ammonium chloride

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The author studied the influence of carbon dioxide on the concentration of ammonium, glutamine, and urea in rabbit's blood. He showed that administration of ammonium chloride to rabbits in doses of 0.1 g/kg of body weight 0.25g/kg, 0.4g/kg and 0.5g/kg leads to a corresponding rise of ammonium, glutamine and urea in the blood. When rabbits are placed into a chamber containing 7–8% carbon dioxide, ammonium is neutralized with simultaneous increase in the formation of glutamine and urea. Inspiration of carbon dioxide prevents cramps and death in rabbits after administration of large doses of ammonium chloride.

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Authors and Affiliations

  1. Department of Biochemistry, Smolensk Medical Institute, USSR

    N. B. Kozlov

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  1. N. B. Kozlov
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Kozlov, N.B. The effect of carbon dioxide gas on the content of ammonia, glutamine, and urea in the blood of amimals after injection of solutions of ammonium chloride. Bull Exp Biol Med 50, 1048–1052 (1961). https://doi.org/10.1007/BF00784877

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  • DOI: https://doi.org/10.1007/BF00784877

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