Bulletin of Experimental Biology and Medicine

, Volume 50, Issue 4, pp 1026–1029 | Cite as

Hematopoiesis and vitamin B12 content in dogs after gastrectomy and in experimental hepatitis

  • O. A. Korolenko
Pathological Physiology and General Pathology


Experimental hepatitis was induced in gastrectomized dogs by the intramuscular injection of yellow phosphorus. Hepatitis development was associated with pronounced macrocytic anemia and disturbance of the B12 storing liver function. All these changes were only temporary. No transition to the megaloblastic type of hematopoiesis was observed. Analogous phenomena developed in dogs with experimental hepatitis and intact stomachs. Moreover, formations of the Heinz bodies type appeared in the erythrocytes as a result of the yellow phosphorus injection.


Public Health Phosphorus Hepatitis Anemia Liver Function 
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Literature Cited

  1. 1.
    Ts. I. Abakeliya, Soobshcheniya AN Gruz. SSR14, 10, 629 (1953).Google Scholar
  2. 2.
    G. A. Alekseev, Klin. Med. 11, 15 (1954).Google Scholar
  3. 3.
    G. A. Alekseev, Problemy Gematol. i Perelivaniya Krovi 5, 12 (1956).Google Scholar
  4. 4.
    A. A. Bagdasarov, P. M. Al'perin, M. Ya. Anshevits, et al., Problemy Gematol. i Perelivaniya Krovi 5, 3 (1956).Google Scholar
  5. 5.
    A. A. Bagdasarov, Vestnik AMN SSSR 3, 37 (1959).Google Scholar
  6. 6.
    Kh. Kh. Vlados, A. A. Bagdasarov, M. S. Dul'tsin, et al., in: Contemporary Problems of Hematology and Blood Transfusion [in Russian] (Moscow-Leningrad, 1936). Nos. 13–14, p. 41.Google Scholar
  7. 7.
    A. I. Gol'dberg, Transactions of the Fourth Pavlov Conference of the Tomsk Medical Institute [in Russian] (1954) p. 73.Google Scholar
  8. 8.
    A. I. Gol'dberg, Terap. Arkh. 1, 65 (1955).Google Scholar
  9. 9.
    A. I. Gol'dberg, Problemy Gematol. i Perelivaniya Krovi 2, 26 (1956).Google Scholar
  10. 10.
    N. T. Fokina, Problemy Gematol. i Perelivaniya Krovi 6, 33 (1956).Google Scholar
  11. 11.
    N. T. Fokina, Terap. Arkh. 5, 30 (1957).Google Scholar
  12. 12.
    J. Bence, Z. klin. Med.130, 275 (1936).Google Scholar
  13. 13.
    R. A. Bussabarger, F. P. Cuthbert, and A. C. Ivy, J. Lab. and Clin. Med.24, 24 (1938).Google Scholar
  14. 14.
    R. A. Bussabarger, A. C. Ivy, and H. S. Wigodsky, et al., Ann. Intern. Med.13, 1028 (1939).Google Scholar
  15. 15.
    W. B. Castle, Science82, 159 (1935).Google Scholar
  16. 17.
    G. Fontés, J. Kunlin, and L. Thivolle, Sang10, 433 (1936).Google Scholar
  17. 18.
    G. B. J. Glass, Therapie,10, 3 425 (1955).Google Scholar
  18. 19.
    G. B. J. Glass, L. C. Lillick, and L. J. Boyd, Blood9, 1127 (1954).Google Scholar
  19. 20.
    A. C. Ivy, O. Richter, and M. C. Kim, Am. J. Physiol.101, 59 (1932).Google Scholar
  20. 21.
    M. Rachmilewitz, Y. Stein, and J. Aronovitch, et al., Arch. Intern. Med.101, 1118 (1958).Google Scholar
  21. 22.
    E. E. Reimer, Wien. Z. inn. Med.33, 303, (1952).Google Scholar
  22. 23.
    M. Tomoda, Chirurg25, 49 (1954).Google Scholar

Copyright information

© Consultants Bureau Enterprises, Inc. 1961

Authors and Affiliations

  • O. A. Korolenko
    • 1
    • 2
  1. 1.Department of Pathophysiology of the Tomsk Medical InstituteTomskUSSR
  2. 2.Department of Biochemistry of the Tomsk Medical InstituteTomskUSSR

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