Bulletin of Experimental Biology and Medicine

, Volume 54, Issue 4, pp 1138–1141 | Cite as

The mechanism of the action of para-aminobenzoic acid on the organism

Report 1. The effect of administration of para-aminobenzoic acid on the gas exchange and temperature of the body
  • Yu. F. Udalov
Pharmacology
  • 72 Downloads

Summary

A study was made of the effect exerted by para-aminobenzoic acid on gaseous exchange and body temperature of albino rats. As demonstrated, its administration decreases oxygen uptake; this phenomenon is especially pronounced in animals to which an oxygen-deficient gaseous mixture is given for respiration. Para-aminobenzoic acid administration also leads to a rise in the body temperature. The body temperature is not reduced in combined administration of para-aminobenzoic acid and thyroidin. Para-aminobenzoic acid given in doses of from 0.2 to 1.0 g reducted the BMR and metabolism at rest in healthy persons investigated. The mechanism of this phenomenon requires a further study.

Keywords

Oxygen Public Health Body Temperature Gaseous Mixture Gaseous Exchange 

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Copyright information

© Consultants Bureau Enterprises, Inc. 1963

Authors and Affiliations

  • Yu. F. Udalov

There are no affiliations available

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