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Laws of growth of mammary gland tissues in in vivo culture

  • Experimental Biology
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Summary

Mammary gland epithelium from dogs was studied by the method of in vivo tissue culture developed by F. M. Lazarenko. In the implants of nonpregnant recipients with intact or excized ovaries the growth of the donor lacrimal gland epithelium is inhibited. Epithelium of the donor gland grows well according to the inflammatory proliferative type in the implants of hypophysectomized females. In the implants of pregnant recipients new secreting lobules grow from the donor mammary gland epithelium; their function is analogous to that of the recipient's gland proper (in form and time).

Thus, in the process of evolution the lacrimal gland epithelium lost the protective properties of cutaneous epithelium, from which it had originated, and its growth and differentiation became dependent on the body hormonal correlations.

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Khlystova, Z.S. Laws of growth of mammary gland tissues in in vivo culture. Bull Exp Biol Med 55, 569–571 (1964). https://doi.org/10.1007/BF00784422

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  • DOI: https://doi.org/10.1007/BF00784422

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