Summary
Mammary gland epithelium from dogs was studied by the method of in vivo tissue culture developed by F. M. Lazarenko. In the implants of nonpregnant recipients with intact or excized ovaries the growth of the donor lacrimal gland epithelium is inhibited. Epithelium of the donor gland grows well according to the inflammatory proliferative type in the implants of hypophysectomized females. In the implants of pregnant recipients new secreting lobules grow from the donor mammary gland epithelium; their function is analogous to that of the recipient's gland proper (in form and time).
Thus, in the process of evolution the lacrimal gland epithelium lost the protective properties of cutaneous epithelium, from which it had originated, and its growth and differentiation became dependent on the body hormonal correlations.
Similar content being viewed by others
Literature Cited
M. M. Averbakh. Proceedings of the 3rd Scientific Conference of the Institute of Physical Education and School Hygiene on Age Morphology, Physiology, and Biochemistry [in Russian], p. 561, Moscow, 1959.
D. I. Golovin. Arkh. pat.,1, 59 (1952).
K. L. Kitaeva and F. A. Rakina. Trudy Khabarovsk. med. inst., 13, 125 (1954).
F. M. Lazerenko. Principles of Growth and Transformation of Tissues and Organs after Implantation in Vivo [in Russian], Moscow, 1959.
Z. S. Margulis. Research into the Dynamics of Development [in Russian], Vol. 10, p. 173. Moscow, 1935.
I. V. Markelova. Doklady Akad. Nauk SSSR72, 1, 221 (1950).
I. V. Markelova. Byull. éksper. biol.,6, 58 (1952).
I. V. Markelova. Trudy Moskovsk. obshch. ispytatelei pirody. Biol. otedel.2, 23 (1961).
Z. S. Khlystova. Trudy Orenburgsk. med. inst., 6, 265 (1958).
N. R. Tsarapkin. Uspekhi sovr. biol.27, 1, 15 (1949).
D. K. Shur. Byull. éksper. biol.22, 8, 15 (1946).
L. Desclin, C. R. Soc. Biol., 1939, Vol. 131, p. 837.
F. Hisaw and E. Aswood, Cited by V. E. Petersen.
A. Lewis and C. Turner. Cited by V. E. Petersen.
V. E. Petersen. Uspekhi sovr. biol.20, 2, 221 (1945).
R. Reece and S. Leonard, Proc. Soc. exp. Biol. (N. Y.), 1939, Vol. 42, p. 200.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Khlystova, Z.S. Laws of growth of mammary gland tissues in in vivo culture. Bull Exp Biol Med 55, 569–571 (1964). https://doi.org/10.1007/BF00784422
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00784422