Summary
The results of studying the karyotype of cells obtained from a monolayer culture of human cancer of the stomach (Cave strain) are presented. The relative cytogenetic homogeneity of the cells of this strain was established: The number of chromosomes in 81% of the cells varied from 58 to 62 with a pronounced peak within the range of 58–60. A characteristic chromosome (long, subtelocentric), revealed in the majority of the cells, was a marker for the given strain. Some cells had an additional marker chromosome — a large and acrocentric one. It is assumed that monosomia and trisomia in individual chromosomes are present. In some cells small chromosome fragments were revealed.
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Ugryumov, E.P., Tsoneva-Maneva, M.T. A study of the karotype of a monolayer culture of carcinoma of the human stomach. Bull Exp Biol Med 55, 560–564 (1964). https://doi.org/10.1007/BF00784420
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DOI: https://doi.org/10.1007/BF00784420