Summary
As demonstrated in chronic experiments on dogs, prolonged irritation of mechanoceptors of the intestinal wall caused development of dynamic intestinal obstruction. Inhibition of the motor function is accompanied by a characteristic triad — vomiting, anorexia and depression.
Motor inhibition is caused by two different reflexes. The arc of one of them is blocked in the sympathetic ganglia and may be interrupted by administration of a gangliolytic (dicoline). The second route of reflex inhibition evidently passes through the higher portions of the central nervous system, since the morphine-thiopenthal anesthesia interrupts the arc of this reflex.
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Gal'perin, Y.M. Stimulation of the mechanoreceptors of the intestinal wall as a cause of dynamic intestinal obstruction. Bull Exp Biol Med 55, 515–517 (1964). https://doi.org/10.1007/BF00784405
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DOI: https://doi.org/10.1007/BF00784405