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Functional and morphological changes produced by profound general refrigeration in the central nervous system after the heart has been excluded from the general circulation

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

At normal body temperatures, exclusion of the heart from the circulation for as long as 7 minutes is apt to lead to irreversible changes and death (two out of three). When the body temperature is lowered to 24–28°, even 19 minutes of heart exclusion from the circulation produces mostly only reversible central nervous system alterations. Usually, by the second postoperative day, no functional changes of the nervous system could be observed.

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Literature Cited

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Authors and Affiliations

  1. Department of Nervous Diseases Faculty 2d Surgical Division and Department Pathological Physiology, S. M. Kirov Military Medical Academy, Leningrad

    G. A. Akimov, V. I. Burakovsky & E. V. Gubler

Authors
  1. G. A. Akimov
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  2. V. I. Burakovsky
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  3. E. V. Gubler
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Akimov, G.A., Burakovsky, V.I. & Gubler, E.V. Functional and morphological changes produced by profound general refrigeration in the central nervous system after the heart has been excluded from the general circulation. Bull Exp Biol Med 43, 749–752 (1957). https://doi.org/10.1007/BF00784342

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  • DOI: https://doi.org/10.1007/BF00784342

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