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Protracted heterotranslantation of the mouse tumor to rats

Article 1: a study of the biological properties of mouse ascitic adenocarcinoma serially transplanted to rats

  • Pharmacology
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Over 100 intra-abdominal heterotransplantations of Ehrlich's ascitic adenocarcinona to 3–5-day old rats were performed. Although the essential nature of the initial ascitic cancer was preserved for 16 months, some of its biological effects on mice and rats were altered, e.g., the mice did not form a large amount of ascitic fluid. In rats two weeks old and older, the growth rate of the heterogeneous implantations decreased from that of the original virulent mouse tumor.

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Podoplelov, I.I. Protracted heterotranslantation of the mouse tumor to rats. Bull Exp Biol Med 43, 708–710 (1957). https://doi.org/10.1007/BF00784333

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  • DOI: https://doi.org/10.1007/BF00784333

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