Summary
By perfusing an isolated intestinal loop in cats anesthetized by urethane, reflex changes of blood pressure and respiration produced by hexenal, acetylcholine and nicotine on intestinal interoceptors were studied. Strong (10%) and weak 2–5 mg%) solutions of hexenal affect the interoceptors, lowering their excitability after prolonged contact. A reflex from the interoceptors probably plays a part in the mechanism of hexenal anesthesia.
Similar content being viewed by others
Literature Cited
Anikina, N. A., Byull. Eksptl. Biol. i Med., 1956, 42, No. 8, 6–12. Original Russian pagination. See C. B. translation.
Asratyan, S. N., and Kuznetsov, A. I., Fiziol. Zhur. SSSR, 1938, 24, No. 5, 964–981.
Bukhtiyarov, A. G., in the book Mechanisms of Pathological Reactions, In Russian. in 16–20, pp. 253–262, Leningrad. 1950.
Galkin, V. C., in the book:Mechanisms of Pathological Reactions, In Russian, pp. 4–38, Leningrad, 1955.
Lebedeva, V. A., Byull. Eksptl. Biol. i Med., 1952, 34, No. 11, 17–21.
Fedotov, Yu. P., in the book:Trans. Izhevsk Med. Inst., In Russian. v. 6, p. 186, Izhevsk, 1948.
Chernigovsky, V. N., The Afferent Systems of the Internal Organs, Kirov, In Russian. 1943.
Alvarez-Buylla R., Arch. Instit. Cardiol. Mexico, 1951, v. 21, p. 724. cited by Landgren S., Liljestrand G., and Zotterman I.
Dawes G. S., and Comroe J. H., Physiol. Rev., 1954, v. 34, p. 167–201.
Emmelin N. Acta Physiol. Scand., 1941 v. 2, p. 289–310.
Genuit H., and Labenz K. Arch. exper. Path. u. Pharmakol., 1941, Bd. 198, S. 369–384.
Landgren S., Liljetrand G., and Zotterman J. Arch exp. Path. u. Pharmacol., 1953, Bd. 219, S. 185–191.
Ibid, Acta Physiol. Scand., 1954, V. 30, pp. 149–160.
Paintal A. S. in: XX Internat. physiol. congress I. Abstracts of reviews. Brussels, 1956, pp. 78–89.
Robertson I. D., Swan A. A., and Whitteridge D., J. Physiol., 1955, v. 128, p. 6.
Tatum A. L., Physiol. Rev., 1939, v. 19, p. 472–502.
Whitteridge D. and Bulbring E., J. Pharmacol. Exper. Therap., 1944, v. 81, p. 340–359.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lebedeva, V.A. On the mechanism of action of hexenal. Bull Exp Biol Med 43, 678–682 (1957). https://doi.org/10.1007/BF00784326
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00784326