The effect of oxygen lack and prolonged radial acceleration on animals

  • N. A. Agadzhanyan
  • A. R. Mansurov
Pathological Physiology and General Pathology


In conditions of oxygen defiency in raising the animals to the altitude of 2,000–10,000 m a study was made of the conditioned reflex reactions of respiration and cardiac activity; an inquiry was also made into the character of the changes occurring in the roentgenological picture of the chest organs in relation to various acceleration values created in rotation on a centrifuge. As established, in conditions of oxygen deficiency at the altitude of 6,000–9,000 m the vegetative components of the conditioned reflexes are depressed almost completely and are replaced by the unconditioned ones, manifested in a marked intensification of the respiratory function and of the cardiac activity. At the altitudes of over 9,000 m there occur marked disturbances of these functions, manifested in periodic respiration and cardiac arrhythmia.

With the action of the centripetal forces on the organism in the direction head tail a reduction of the size and of the intensity of the cardiac shadow takes place, as well as a shift in the position and deformation of internal organs. The character and the extent of the changes in the roentgenological picture of internal organs depends both on the value and the duration of the acting acceleration, and on the initial functional state of the central nervous system.


Cardiac Arrhythmia Conditioned Reflex Oxygen Deficiency Cardiac Activity Direction Head 
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Copyright information

© Consultants Bureau Enterprises, Inc. 1963

Authors and Affiliations

  • N. A. Agadzhanyan
  • A. R. Mansurov

There are no affiliations available

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