Summary
The authors conducted a histochemical study of the distribution of “Kul' chitskii cells” and their saturation with the granules in various laboratory animals. The argentaffin and chromaffin reaction were determined with a parallel diazo reaction. An uneven distribution of “Kul'chitskii cells” along the intestine was revealed. The highest density of the cells and the greatest granule saturation were observed in the duodenal mucous membrane of cats, rabbits, guinea pigs, white rats, white mice, monkeys and chicks. The content of argentaffin granules is slightly decreased in the cellular protoplasma of fasting guinea pigs, but even in animals dead of hunger they do not disappear completely. After intraperitoneal injection of reserpine, argentaffin granules vanish in normal animals, but not in fasting ones.
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Literature Cited
N. K. Kul'chitskii, (Kultschitzky N), Arch. microskop. Anatomie u. Entw. 49, 7 (1897).
Yu. M. Lazovskii, Zhur. Éksptl. Med. 1, 2, 93 (1928).
A. Pearse, Histochemistry, 1956 [Russian translation].
E. Benditt and R. Wong, J. Exper. Med. 105, 6, 509 (1957).
B. Brodie, A. Pletscher and P. Shore, Science, 122, 3177, 968 (1955).
C. Clark, H. Weissbach and S. Udenfriend, J. Biol. Chem. 210, 139 (1954).
P. Detril, Presse méd. 64, 49, 1138 (1956).
O. Eber and F. Lembeck, Pflügers. Arch. 265, 6, 263 (1958).
V. Erspamer and B. Asero, Nature. 169, 4306, 800 (1952).
F. Feyrter and Klaus-Unna, Virch. Arch. 298, 187 (1937).
J. Gaddum and N. Giarman, Brit. J. Pharm. 11, 88 (1956).
A. Gebauer and K. Kümelin, Dtsch. med. Wschr. 83, 15, 620 (1958).
L. Gennes and M. de Fossey, Presse med. 64, 46, 1066 (1956).
K. Hamlin and F. Fischer, J. Am. Chem. As. 73, 5007 (1951).
K. Hegglin and H. Langemann, Helv. med. acta 4 5, 463 (1955).
L. Heilmeyr and K. Clotten, Deutsch. med. Wschr. 83, 15, 617 (1958).
O. Hornykiewicz, Acta Neuroveget. 13, 1, 111 (1956).
P. Isler and G. Hedinger, Schw. med. Wschr. 1, 4 (1953).
H. Kahr, Acta Neuroveget. 1, 99 (1956).
H. Langemann, Schweiz. med. Wschr. 85, 40, 957 (1955).
F. Lembeck, Arch. exper. Path. u. Pharm. 221, 50 (1954).
J. Levy and E. Michel-Ker, Compt. rend. séance Acad. sci. 242, 25, 3007 (1956).
B. Pernow and Waldenstrom, Lancet. 267, 951 (1954).
M. Rapport, A. Green and J. Page, J. Biol. Chem. 176, 1243 (1948).
F. Rowwer and E. Werle, Arch. exp Path. u. Pharm. 230, 6, 552 (1957).
S. Udenfriend, E. Titus and H. Weissbach, J. Biol. Chem. 216, 499 (1955).
G. Zbinden, A. Pletscher and A. Studer, Kl. Wschr. 35, 11, 565 (1957).
G. Zbinden, A. Pletscher and A. Studer, Schw. med. Wschr. 87, 22, 629 (1957).
W. Zilka and P. Köhler, Klin. Wschr. 39, 12, 622 (1957).
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Yakovleva, A.I., Shakhnazarova, N.G. Histochemical investigations of the “Kul' chitskii cells” in the gastrointestinal tract of experimental animals. Bull Exp Biol Med 48, 1028–1032 (1959). https://doi.org/10.1007/BF00783804
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DOI: https://doi.org/10.1007/BF00783804