Skip to main content
SpringerLink
Log in

DNA content of the corneal epithelial cells of rats after x-irradiation

  • Experimental Biology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

In a period of 24–120 h after the irradiation of rats with x-rays in a dose of 700R there is a marked nuclear polymorphism. In the corneal epithelium there appear cells with satellite nuclei and a larger number of binuclear cells. The results of investigations carried out by means of cytospectrophotometry showed that after irradiation the number of polyploid nuclei containing DNA in quantities of 5–8 respectively grows 30% whereas normally it is only 10%. The satellite nuclei contain an insiginficant amount of DNA, which points to their formation from chromosome fragments during atypical karyokinesis. The amount of DNA in the nuclei of binuclear cells varies extensively; the minimum quantity being 1n+1n, the maximum we have noted being 3n+5n.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. I. B. Bychkovskaya, Concerning the biological action of x-rays in small doses [in Russian], Diss. kand., Leningrad (1953).

  2. M. N. Veselkina, Tsitologiya, No. 5 (1962), p. 571.

    Google Scholar 

  3. G. P. Gruzdev, Radiobiologiya, No. 1 (1961), p. 52; No. 3, p. 407.

    Google Scholar 

  4. L. N. Zhinkin, V. Ya. Brodskii, and G. S. Lebedeva, Tsitologiya, No. 5 (1961), p. 514.

    Google Scholar 

  5. L. Ya. Zhorno and L. P. Ovchinnikova, Dokl. AN SSSR, 144, No. 4 (1962), p. 907.

    Google Scholar 

  6. G. S. Strelin, Vestn. rentgenol., Nos. 1–2 (1934), p. 98.

    Google Scholar 

  7. Idem, Dokl. AN SSSR, Novaya seriya, 73, No. 6 (1950), p. 1283.

    Google Scholar 

  8. Idem, Med. radiol.,2, p. 77 (1960).

    Google Scholar 

  9. K. W. Cleland, Nature, 191 (1961), p. 504.

    Google Scholar 

  10. J. Fautrez, E. Pisi, and G. Cavalli, Ibid., 176 (1955), p. 311.

    Google Scholar 

  11. G. Politzer, Pathologie der Mitose. Berlin (1934).

Download references

Author information

Authors and Affiliations

  1. Laboratory of Cell Morphology, Institute of Cytology, USSR Academy of Sciences, Leningrad

    M. N. Veselkina

Authors
  1. M. N. Veselkina
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Veselkina, M.N. DNA content of the corneal epithelial cells of rats after x-irradiation. Bull Exp Biol Med 59, 565–567 (1965). https://doi.org/10.1007/BF00783086

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00783086

Keywords

Search

Navigation