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The influence of zymosan and its fractionation products on the level of properdin in the blood and on the morphology of organs and tissues

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Intravenous injection into mice of zymosan and fractions isolated from it led to a reduction of properdin titer and to dystrophic changes mainly in the liver. By the time the blood properdin titer had returned to normal a considerable proliferative reaction of the reticulo-endothelial cells had occurred. These changes were of the same type whether zymosan, glucan, or glucomannic fractions, all partially or completely inactive with respect to the properdin system in vitro were administered.

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Authors and Affiliations

  1. Central Order of Lenin Institute of Hematology and Blood Transfusion, Moscow

    R. A. Rutberg, G. I. Loseva, N. M. Nemenova & V. N. Malanina

Authors
  1. R. A. Rutberg
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  2. G. I. Loseva
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  3. N. M. Nemenova
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  4. V. N. Malanina
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Rutberg, R.A., Loseva, G.I., Nemenova, N.M. et al. The influence of zymosan and its fractionation products on the level of properdin in the blood and on the morphology of organs and tissues. Bull Exp Biol Med 57, 505–509 (1964). https://doi.org/10.1007/BF00782527

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  • DOI: https://doi.org/10.1007/BF00782527

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