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Changes in the liver in animals with experimentally induced splenic disease

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

It was shown in experiments on rabbits that development of a pathological process in the spleen related to impaired circulation in the lienal vein led to the development of annular cirrhosis of the liver. The cirrhotic process was found to be more marked when the splenic injuries occurred in association with previous sensitization of the animals with horse serum and their infection with an attenuated culture ofStreptococcus viridans.

Mechanisms governing these effects require further study.

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Literature Cited

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Authors and Affiliations

  1. Pediatric Clinic, Pathophysiological Department M. F. Vladimirskii Moscow Regional Scientific Research Clinical Institute, Institute of Human Morphology AMN SSSR, Moscow

    M. I. Olevskii, Yu. M. Gal'perin & V. A. Odinokova

  2. Department of Morbid Anatomy M. F. Vladimirskii Moscow Regional Scientific Research Clinical Institute, Institute of Human Morphology AMN SSSR, Moscow

    M. I. Olevskii, Yu. M. Gal'perin & V. A. Odinokova

Authors
  1. M. I. Olevskii
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  2. Yu. M. Gal'perin
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  3. V. A. Odinokova
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Olevskii, M.I., Gal'perin, Y.M. & Odinokova, V.A. Changes in the liver in animals with experimentally induced splenic disease. Bull Exp Biol Med 57, 501–504 (1964). https://doi.org/10.1007/BF00782526

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  • DOI: https://doi.org/10.1007/BF00782526

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