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The antigenic structure of the rous sarcoma communication I. Detection of the specific rous sarcoma antigen by the precipitation test in agar

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

With the aid of the precipitation reaction in agar and the ring-precipitation test the authors compared the antigenic composition of Rous sarcoma with that of the organs of healthy chickens (liver, kidney, spleen, subcutaneous cellular tissue, muscles, etc.), transplantable chicken sarcoma MKh-659 (primarily induced with methylcholanthrene), and normal chicken serum. Evidence was obtained that it is possible to detect the specific antigen in Rous sarcoma extracts only with the aid of precipitation in agar, while the ring precipitation reaction does not permit differentiation of this antigen.

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Authors
  1. A. I. Gusev
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Additional information

Division of Immunology and Oncology (Head-Active Member AMN SSSR L.A. Zil'ber) of the N. F. Gamalei Institute of Epidemiology and Microbiology (Director-Prof. S. N. Muromtsev)

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Gusev, A.I. The antigenic structure of the rous sarcoma communication I. Detection of the specific rous sarcoma antigen by the precipitation test in agar. Bull Exp Biol Med 49, 601–604 (1960). https://doi.org/10.1007/BF00782115

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  • DOI: https://doi.org/10.1007/BF00782115

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