Bulletin of Experimental Biology and Medicine

, Volume 49, Issue 6, pp 550–553 | Cite as

The independence of mechanisms regulating the diameter of regional arteries of the brain (internal carotid and vertebral) and of the pial arteries

  • G. I. Mchedlishvili


The author estimated the resistance in the internal carotid and vertebral arteries from measurements of arterial blood pressure in the aorta and the circle of Willis. These arteries become constricted when the tracheotomy tube is temporarily occluded. Under these conditions the pial arteries may dilate independently of the regional arteries of the brain, while the arterial pressure in the aorta and the circle of Willis remains unchanged. The same changes occur in response to local application of strychnine to the surface of the brain. Thus, the mechanism controlling the diameters of the pial arteries are independent of the mechanism regulating the state of the regional arteries of the brain (internal carotids and vertebrals).


Public Health Blood Pressure Arterial Pressure Arterial Blood Pressure Vertebral Artery 
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Copyright information

© Consultants Bureau Enterprises, Inc. 1960

Authors and Affiliations

  • G. I. Mchedlishvili
    • 1
  1. 1.Division of Pathologic Physiology. Institute of PhysiologyAcademy of Sciences of the Georgian SSRTbilisi

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