Summary
Changes in the total gas exchange during healing of skin wounds were studied in albino rats in conditions of varying functional activity of the higher portions of their CNS. Administration of phenamine, which enhanced the cortical excitation process brought about a more intense exchange thus contributing to a more rapid healing of the wound. In these conditions there was a rise in the activity of cellular elements of mesenchymal nature, and also a more rapid alteration of individual phases of inflammation and regeneration. Barbamyl, while enhancing the inhibition in the cerebral cortex, led to reduction and inversion of the total gas exchange, depressing regeneration process in the skin.
Similar content being viewed by others
Literature Cited
K. M. Bykov, In the book: Certain Problems of Physiology, Clinical Aspects, and Morphology. Kuibyshev, p. 6 (1958).
V. G. Eliseev, Trudy 1-go Moskovsk. med. inst.,2, p. 7 (1957).
R. P. Ol'nyanskaya and L. A. Isaakyan, Zh. vyssh. nervh. deyat., 3, p. 408 (1956).
R. P. Ol'yanskaya and G. A. Tubitsina, Dokl. AN SSSR 138, 5, p. 1245 (1961).
B. V. Pavlov, Fiziol. zh. SSSR, 3, p. 271 (1950).
M. I. Prokhorova and Z. N. Tupikova, in the book: Carbohydrates and Carbohydrate Metabolism in Animals and Plants [in Russian], Moscow, p. 120 (1959).
P. E. Syrkina, Gas Analysis in Medical Practice [in Russian], Moscow (1956).
V. K. Faddeeva, Experimental Investigations of the Effect of Phenamine on the Work of the Higher Divisions of the Central Nervous System (On the Work of the Cerebral Cortex). Diss. dokt. [in Russian], Moscow (1953).
G. V. Khomullo, In the book: Problems of Regeneration and Cell Division [in Russian], Moscow, p. 57 (1959).
G. V. Khomullo, Byull. éksper. biol. 2, p. 97 (1962).
J. Chutna, Csl. Biol. (1954), v. 3, p. 10.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Khomullo, G.V. Changes in gas exchange in animals during regeneration under the effect of phenamine and barbamyl. Bull Exp Biol Med 59, 88–91 (1965). https://doi.org/10.1007/BF00782075
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00782075