Summary
It was demonstrated that the DNA preparations can be precipitated by normal rabbit sera; no nucleic acid specificity was revealed in such cases. The capacity of DNA to precipitate with normal rabbit sera did not depend on the amount of protein admixtures in the DNA preparations and was determined by the polymeric state of the DNA molecule.
Normal precipitants to DNA are unstable when stored at+4°C.
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Literature Cited
V. Yu. Klimov and K. G. Chamova, Some Problems of Theoretical and Clinical Medicine [in Russian] (1961), No. 1, p. 13.
A. S. Spirin, Biokhimiya (1958), No. 5, p. 656.
A. S. Spirin, L. P. Gavrilova and A. N. Belozerskii, (1959), No. 4, p. 600.
D. M. Spitkovskii, Biofizika (1958), No. 3, p. 396.
B. D. Timakov, A. G. Skavronskaya and N. B. Borisova et al., Zh. mikrobiol. (1963), No. 1, p. 5.
K. G. Chamova, Byull. éksper. biol. (1957), No. 10, p. 91.
E. Chargaff and S. Zamenhof, J. biol. Chem. (1948), v. 173, p. 327.
H. R. G. Deicher, H. G. Holman and H. G. Kunke., J. Exp. Med. (1959), v. 109, p. 97.
D. Lackman, S. Mudd, and M. G. Sevag et al., J. Immunol. (1941), v. 40, p. 1.
C. G. Leonard and C. B. Thorne, J. Immunol (1961), v. 87, p. 175.
H. Masamune, S. Tsuiki and E. Kitabatake et al., Tohoku J. exp. Med. (1955), v. 61, p. 171.
W. C. Robbins, H. R. Holman, and H. Deicher et al., Proc. of the Society for Exp. Biol. and Med. (1957), v. 96, p. 575.
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Klimov, V.Y., Chamova, K.G. DNA precipitation by normal rabbit sera. Bull Exp Biol Med 59, 78–80 (1965). https://doi.org/10.1007/BF00782072
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DOI: https://doi.org/10.1007/BF00782072