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The effect of anesthetics on the bulbar and spinal vasomotor formations

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Vascular response to local stimulation of various components of the bulbar vasomotor center and of the lateral spinal cord horns (Th7–Th8) were recorded in decerebrated and spinal cats. Histological control was carried out in all the experiments. Depression of the vascular responses by

In comparing the efficacy of the depressive effect produced by the anesthetics at the bulbar and the spinal level in experiments on the same animal it appeared that the minimal doses of urethane and nembutal primarily depressed the pressor effects from the bulbar vasomotor structures.

The data obtained may evidently be explained by the peculiarities of morphological structure of the vasomotor formations and their tracts, as well as by a different sensitivity of the reticular neurones to urethane and nembutal.

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Kovalev, G.V. The effect of anesthetics on the bulbar and spinal vasomotor formations. Bull Exp Biol Med 59, 66–70 (1965). https://doi.org/10.1007/BF00782069

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  • DOI: https://doi.org/10.1007/BF00782069

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