Skip to main content
Log in

The rate of formation of phage resistant mutants in the cell population of virulent strains of plague bacilli

  • Pathological Physiology and General Pathology
  • Microbiology and Immunology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The rate of formation of phage resistant mutants in the cell population of virulent strains of plaque bacilli.

A continued study of the frequency of formation of bacteriophage resistant mutants in the cell populations of virulent strains, as well as an analysis of colonies, isolated with the aid of the replica plaring technique in the absence of the destructive factor (bacteriophage) demonstrated mutations of individual cells to have an adaptive nature. The frequency of bacteriophage resistant mutant formation in the virulent plague strains constitutes 1·10−9.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature Cited

  1. A. I. Volosivets, Bull. eksper. biol., No. 9 (1963), p. 81; No. 11, p. 107.

    Google Scholar 

  2. N. G. Zhukov-Verezhnikov and A. P. Pekhov, In “Directions for Microbiology, Clinical and Epidemiological Consideration of Infectious Diseases,” Vol. 1 (1962), p. 560.

  3. E. I. Korobkova, Vestn. mikrobiol. Ch. 1–2 (1937), p. 3.

    Google Scholar 

  4. G. N. Lenskaya, “Variation in Plague Bacillus.” Candidate's Thesis, Saratov (1946).

  5. V. M. Tumanskii, “Microbiology of Plague,” Moscow (1958).

  6. J. Lederberg, and E. M. Lederberg, J. Bact., Vol. 63 (1952), p. 399.

    Google Scholar 

  7. S. E. Luria and M. Delbrück, Genetics, Vol. 28 (1943), p. 491.

    Google Scholar 

  8. H. B. Newcombe,Ibid., Vol. 33 (1948), p. 447.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Volosivets, A.I. The rate of formation of phage resistant mutants in the cell population of virulent strains of plague bacilli. Bull Exp Biol Med 57, 318–321 (1964). https://doi.org/10.1007/BF00781917

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00781917

Keywords

Navigation