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Effect of changes in mediator metabolism on the development of cardiac hypertrophy

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Substances creating prevalence of the catecholamine system (iprazid) or of the acetylcholine system (proserine, reserpine) were administered to rats with experimental coarctation of aorta. The evidence proved that proserine and reserpine increase the degree of hypertrophy. The results thus obtained are examined in the light of interrelations between the contractile function level of the myocardium and its hypertrophy.

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Literature Cited

  1. F. Z. Meerson, Compensatory Hyperfunction and Failure of the Heart [in Russian], Moscow (1960).

  2. W. Lee and F. Shideman, Science, Vol. 129 (1959), p. 967.

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Authors and Affiliations

  1. Institute of Normal and Pathological Physiology, AMN SSSR, Moscow

    F. Z. Meerzon & L. S. Rozanova

Authors
  1. F. Z. Meerzon
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  2. L. S. Rozanova
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Meerzon, F.Z., Rozanova, L.S. Effect of changes in mediator metabolism on the development of cardiac hypertrophy. Bull Exp Biol Med 57, 282–284 (1964). https://doi.org/10.1007/BF00781908

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  • DOI: https://doi.org/10.1007/BF00781908

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