Bulletin of Experimental Biology and Medicine

, Volume 45, Issue 4, pp 499–502 | Cite as

The significance of complete decortication in the development of anaphylactic shock in dogs

  • G. K. Vasil'eva
Microbiology and Immunity


Following unilateral decortication, the condition of sensitization and anaphylactic shock develops in dogs with the same doses of antigen (horse serum) as in intact animals. Fifteen days after removal of the second hemisphere the intensity of the shock reaction, appearing as a result of introduction of the same dose of the antigen was greatly decreased. One month after complete decortication the manifestations of anaphylaxis were even less pronounced. The intensity of anaphylactic shock was especially low six months after bilateral decortication. This demonstrates that bilateral decortication decreases the reactivity of the animal organism to the antigenic stimulus.


Public Health Horse Serum Intact Animal Anaphylactic Shock Antigenic Stimulus 
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Copyright information

© Consultants Bureau, Inc. 1958

Authors and Affiliations

  • G. K. Vasil'eva
    • 1
    • 2
  1. 1.Physiologic LaboratoryAcad. Sci. USSRKuibyshevUSSR
  2. 2.Department of Pathologic PhysiologyKuibyshev Medical InstituteKuibyskevUSSR

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